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Moraga F, Janciauskiene S

Cerella C, Coppola S, DAlessio M, De Nicola M, Magrini A, Bergamaschi A et al

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The transcription factors ATF4 and Nrf2 couple ER stress to a general cellular response that increases the production of glutathione by increasing amino-acid metabolism (Cullinan et al , 2003

Understanding the complex interplay between hypoxia-induced signalling pathways, oxidative stress and inflammatory responses will provide a better insight into the underlying mechanisms of disease pathogenesis

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